从实验室到市场:光声成像的产业化进程

Yasha Saxena; Chulhong Kim; Yao Junjie

doi:10.3788/IRLA201746.1103001

从实验室到市场:光声成像的产业化进程

doi: 10.3788/IRLA201746.1103001

1.
Department of Biomedical Engineering,Duke University,Durham,USA;
2.
Departments of Creative IT Engineering and Electrical Engineering,Pohang University of Science and Technology(POSTECH),Pohang,Republic of Korea

基金项目:

美国杜克大学MEDx基金

详细信息

作者简介:
Yasha Saxena (1990-),女,硕士生,主要从事光声成像技术方面的研究。Email:yasha.saxena@duke.edu

中图分类号: O439

From bench to market:commercialization of photoacoustic imaging

1.
Department of Biomedical Engineering,Duke University,Durham,USA;
2.
Departments of Creative IT Engineering and Electrical Engineering,Pohang University of Science and Technology(POSTECH),Pohang,Republic of Korea

More Information

Author Bio:
Yasha Saxena (1990-),女,硕士生,主要从事光声成像技术方面的研究。Email:yasha.saxena@duke.edu

摘要: Photoacoustic imaging (PAI) or optoacoustic imaging, the modern application of an ancient physical discovery to biomedical imaging, is without doubt one of the most exciting imaging technologies that has drawn increasing attention from biomedical specialists. In PAI, the rich contrast of optical excitation is seamlessly combined with the high spatial resolution and large penetration depth of ultrasonic detection to produce clear images of optically scattering biological tissues. As a complementary imaging modality that surpasses the territory of traditional microscopic optical imaging, PAI has been explored for numerous biomedical studies, and hence enthusiastically embraced by researchers around the globe who have attested to its unique imaging capabilities, namely the deep penetration and functional sensitivity. Not surprisingly, as the market clearly sees the promise, the commercial production of PAI systems has grown apace with the technological advancements and clinical applications. The adoption of commercial PAI in research and clinical settings has however seen difficulties, majorly due to costs, regulatory blocks, and competition with mainstream technologies. Here, from a practical standpoint, a wide range of commercial PAI systems currently available in the market were introduced, their advantages and disadvantages were analyzed, and the design considerations for targeted applications were emphasized. The key technological, logistical, and clinical issues were also discussed that need to be solved to accelerate the technology translations. By doing so, it is hoped that a clearer picture of the future commercialization of PAI for clinicians, researchers, and industrial entrepreneurs will be presented.
- photoacoustic imaging /
- commercialization /
- oxygenation saturation of hemoglobin /
- tumor imaging /
- breast cancer imaging /
- endoscopy
Abstract: Photoacoustic imaging (PAI) or optoacoustic imaging, the modern application of an ancient physical discovery to biomedical imaging, is without doubt one of the most exciting imaging technologies that has drawn increasing attention from biomedical specialists. In PAI, the rich contrast of optical excitation is seamlessly combined with the high spatial resolution and large penetration depth of ultrasonic detection to produce clear images of optically scattering biological tissues. As a complementary imaging modality that surpasses the territory of traditional microscopic optical imaging, PAI has been explored for numerous biomedical studies, and hence enthusiastically embraced by researchers around the globe who have attested to its unique imaging capabilities, namely the deep penetration and functional sensitivity. Not surprisingly, as the market clearly sees the promise, the commercial production of PAI systems has grown apace with the technological advancements and clinical applications. The adoption of commercial PAI in research and clinical settings has however seen difficulties, majorly due to costs, regulatory blocks, and competition with mainstream technologies. Here, from a practical standpoint, a wide range of commercial PAI systems currently available in the market were introduced, their advantages and disadvantages were analyzed, and the design considerations for targeted applications were emphasized. The key technological, logistical, and clinical issues were also discussed that need to be solved to accelerate the technology translations. By doing so, it is hoped that a clearer picture of the future commercialization of PAI for clinicians, researchers, and industrial entrepreneurs will be presented.
- photoacoustic imaging /
- commercialization /
- oxygenation saturation of hemoglobin /
- tumor imaging /
- breast cancer imaging /
- endoscopy

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从实验室到市场:光声成像的产业化进程

doi: 10.3788/IRLA201746.1103001

作者简介:
Yasha Saxena (1990-),女,硕士生,主要从事光声成像技术方面的研究。Email:yasha.saxena@duke.edu

From bench to market:commercialization of photoacoustic imaging

Author Bio:
Yasha Saxena (1990-),女,硕士生,主要从事光声成像技术方面的研究。Email:yasha.saxena@duke.edu

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从实验室到市场:光声成像的产业化进程

doi: 10.3788/IRLA201746.1103001

1. Department of Biomedical Engineering,Duke University,Durham,USA;

2. Departments of Creative IT Engineering and Electrical Engineering,Pohang University of Science and Technology(POSTECH),Pohang,Republic of Korea

作者简介:
Yasha Saxena (1990-),女,硕士生,主要从事光声成像技术方面的研究。Email:yasha.saxena@duke.edu

English Abstract

From bench to market:commercialization of photoacoustic imaging

1. Department of Biomedical Engineering,Duke University,Durham,USA;

2. Departments of Creative IT Engineering and Electrical Engineering,Pohang University of Science and Technology(POSTECH),Pohang,Republic of Korea

Author Bio:
Yasha Saxena (1990-),女,硕士生,主要从事光声成像技术方面的研究。Email:yasha.saxena@duke.edu

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从实验室到市场:光声成像的产业化进程

doi: 10.3788/IRLA201746.1103001

作者简介: Yasha Saxena (1990-),女,硕士生,主要从事光声成像技术方面的研究。Email:yasha.saxena@duke.edu

From bench to market:commercialization of photoacoustic imaging

Author Bio: Yasha Saxena (1990-),女,硕士生,主要从事光声成像技术方面的研究。Email:yasha.saxena@duke.edu

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从实验室到市场:光声成像的产业化进程

doi: 10.3788/IRLA201746.1103001

1. Department of Biomedical Engineering,Duke University,Durham,USA; 2. Departments of Creative IT Engineering and Electrical Engineering,Pohang University of Science and Technology(POSTECH),Pohang,Republic of Korea

作者简介: Yasha Saxena (1990-),女,硕士生,主要从事光声成像技术方面的研究。Email:yasha.saxena@duke.edu

English Abstract

From bench to market:commercialization of photoacoustic imaging

1. Department of Biomedical Engineering,Duke University,Durham,USA; 2. Departments of Creative IT Engineering and Electrical Engineering,Pohang University of Science and Technology(POSTECH),Pohang,Republic of Korea

Author Bio: Yasha Saxena (1990-),女,硕士生,主要从事光声成像技术方面的研究。Email:yasha.saxena@duke.edu

全文HTML

目录

作者简介:
Yasha Saxena (1990-),女,硕士生,主要从事光声成像技术方面的研究。Email:yasha.saxena@duke.edu

Author Bio:
Yasha Saxena (1990-),女,硕士生,主要从事光声成像技术方面的研究。Email:yasha.saxena@duke.edu

1. Department of Biomedical Engineering,Duke University,Durham,USA;

2. Departments of Creative IT Engineering and Electrical Engineering,Pohang University of Science and Technology(POSTECH),Pohang,Republic of Korea

作者简介:
Yasha Saxena (1990-),女,硕士生,主要从事光声成像技术方面的研究。Email:yasha.saxena@duke.edu

1. Department of Biomedical Engineering,Duke University,Durham,USA;

2. Departments of Creative IT Engineering and Electrical Engineering,Pohang University of Science and Technology(POSTECH),Pohang,Republic of Korea

Author Bio:
Yasha Saxena (1990-),女,硕士生,主要从事光声成像技术方面的研究。Email:yasha.saxena@duke.edu