He Jun, Xu Kexin, Liu Rong, Li Chenxi. Effect of diffuse reflection path-length of near-infrared on sensitivity of glucose concentration detection[J]. Infrared and Laser Engineering, 2016, 45(S1): 29-34. doi: 10.3788/IRLA201645.S104006
| Citation:
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He Jun, Xu Kexin, Liu Rong, Li Chenxi. Effect of diffuse reflection path-length of near-infrared on sensitivity of glucose concentration detection[J]. Infrared and Laser Engineering, 2016, 45(S1): 29-34. doi: 10.3788/IRLA201645.S104006
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Effect of diffuse reflection path-length of near-infrared on sensitivity of glucose concentration detection
- 1.
School of Precision Instrument and Opto-Electronics Engineering,Tianjin University,Tianjin 300072,China
- Received Date: 2016-02-21
- Rev Recd Date:
2016-03-13
- Publish Date:
2016-05-25
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Abstract
Near-infrared photons propagate in the mixed solution of intralipid and glucose and form diffuse reflection. In steady state, the scattered photons at the detection spot include ballistic photons, quasi-ballistic photons, and scattered photons, and part of ballistic photons and scattered photons decrease the detection accuracy of glucose concentration. By Monte Carlo time-domain simulations of 10% and 3%intralipid-glucose solution respectively, different path-length components of diffuse reflection at different detection spots were statistically analyzed. It is shown that both the peak time of the detection time expansion curve and diffuse reflection photons in the average flying time can improve the detection accuracy of the point of floating reference, where the diffuse reflection is the most insensitive to the glucose concentration. Moreover, these photons increase, at the maximum intensity of diffuse reflection, the coefficients of linear dependency between the intensity of diffuse reflection and glucose concentration. Thus, extraction of the diffuse reflection corresponding to this path-length improves the detection sensitivity of glucose concentration.
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References
|
[1]
|
Andre Liemert, Alwin Kienle. Exact and efficient solution of the radiative transport equation for the semi-infinite medium[J]. Scientific Reports, 2013, 3(6):2018. |
|
[2]
|
Aksenova E V, Kokorin D I, Romanov V P. Simulation of multiple scattering in the systems with complicated phase function[J]. Computer Physics Communications, 2015, 196:384-389. |
|
[3]
|
Wang Jiajie, Chen Antao, Han Yiping, et al. Light scattering from an optically anisotropic particle illuminated by an arbitrary shaped beam[J]. Journal of Quantitative Spectroscopy Radiative Transfer, 2015, 167:135-144. |
|
[4]
|
Li Wei, Lin Ling, Bao Lei, et al. Monte Carlo simulation of photon migration in multi-component media[J]. Opt Quant Electron, 2015, 47:1919-1931. |
|
[5]
|
Yang Yue, Chen Wenliang, Shi Zhenzhi, et al. The reference point of floating-reference method for blood glucose sensing[J]. Chinese Optics Letters, 2010, 8(4):421-424. |
|
[6]
|
Wang Dongmin, Lu Qipeng, Ding Haiquan, et al. Effect of path-length variations on PLSR calibration model in noninvasive measurement of blood glucose by mid-infrared spectroscopy[J]. Spectroscopy and Spectral Analysis, 2012, 32(4):930-933. (in Chinese) 王动民, 卢启鹏, 丁海泉, 等. 中红外无创血糖测量中光程变化对PLSR模型的影响研究[J]. 光谱学与光谱分析, 2012, 32(4):930-933. |
|
[7]
|
Michael S Patterson, Chance B, Wilson B C. Time resolved reflectance and transmittance for the non-invasive measurement of tissue optical properties[J]. Applied Optics, 1989, 28(12):2331-2336. |
|
[8]
|
Wang Lihong, Jacques S L, Zheng L. MCML-Monte Carlo modeling of light transport in multi-layered tissues[J].Computer Methods and Programs in Biomedicine, 1995, 47:131-146. |
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