Review of resolution enhancement technologies in quantitative phase microscopy

Gao Peng; Wen Kai; Sun Xueying; Yao Baoli; Zheng Juanjuan

doi:10.3788/IRLA201948.0603007

Volume 48 Issue 6

Jul. 2019

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Article Navigation > Infrared and Laser Engineering > 2019 > 48(6): 603007-0603007(13)

Gao Peng, Wen Kai, Sun Xueying, Yao Baoli, Zheng Juanjuan. Review of resolution enhancement technologies in quantitative phase microscopy[J]. Infrared and Laser Engineering, 2019, 48(6): 603007-0603007(13). doi: 10.3788/IRLA201948.0603007

Citation:

Gao Peng, Wen Kai, Sun Xueying, Yao Baoli, Zheng Juanjuan. Review of resolution enhancement technologies in quantitative phase microscopy[J]. Infrared and Laser Engineering, 2019, 48(6): 603007-0603007(13). doi: 10.3788/IRLA201948.0603007

Review of resolution enhancement technologies in quantitative phase microscopy

doi: 10.3788/IRLA201948.0603007

1.
School of Physics and Optoelectronic Engineering,Xidian University,Xi'an 710171,China;
2.
State Key Laboratory of Transient Optics and Photonics,Xi'an Institute of Optics and Precision Mechanics,Chinese Academy of Sciences,Xi'an 710119,China;
3.
College of Physics and Information Technology,Shaanxi Normal University,Xi'an 710119,China

Received Date: 2019-04-05
Rev Recd Date: 2019-06-15
Publish Date: 2019-06-25

Abstract

Quantitative Phase Microscopy (QPM), which combines phase imaging and optical microscopy, has been acting as a fast, non-destructive, and high-resolution methodology to measure the 3D morphology of reflective samples, as well as the inner structure or the refractive index of transparent samples. Similar to other diffraction-limited imaging systems, QPM suffers from the contradiction between spatial resolution and field of view (FOV). Therefore, how to achieve high spatial resolution in a large FOV has attracted a lot of attentions in the field of optical microscopy. In recent years, people utilized off-axis illumination, speckle illumination, structural illumination, and sub-pixel technology to synthesize a larger numerical aperture (SNA), and consequently enhanced the resolution of QPM. The resolution enhancement technologies of QPM were reviewed in this paper. The advantages and limitations of different methods were analyzed.
- phase imaging,
- resolution enhancement,
- modulated illumination,
- synthetic aperture,
- sub-pixel technology

References

[1]	Platt B C, Shack R. History and principles of Shack-Hartmann wavefront sensing[J]. Journal of Refractive Surgery, 2001, 17(5):S573-S580.
[2]	Bon P, Maucort G, Wattellier B, et al. Quadriwave lateral shearing interferometry for quantitative phase microscopy of living cells[J]. Optics Express, 2009, 17(15):13080-13094.
[3]	Wei Q, Li Y, Vargas J, et al. Principal component analysis-based quantitative differential interference contrast microscopy[J]. Optics Letters, 2019, 44(1):45-48.
[4]	Cuche E, Bevilacqua F, Depeursinge C. Digital holography for quantitative phase-contrast imaging[J]. Optics Letters, 1999, 24(5):291-293.
[5]	Waheb B, Ting-Wei S, Coskun A F, et al. Lensfree on-chip microscopy over a wide field-of-view using pixel super-resolution[J]. Optics Express, 2010, 18(11):11181-11191.
[6]	Kyoohyun K, Hyeok Y, Monica D S, et al. High-resolution three-dimensional imaging of red blood cells parasitized by Plasmodium falciparum and in situ hemozoin crystals using optical diffraction tomography[J]. Journal of Biomedical Optics, 2014, 19(1):011005-011018.
[7]	Marquet P, Depeursinge C, Magistretti P J. Review of quantitative phase-digital holographic microscopy:promising novel imaging technique to resolve neuronal network activity and identify cellular biomarkers of psychiatric disorders[J]. Neurophotonics, 2014, 1(2):020901-020915.
[8]	Mitchison J M. Single cell studies of the cell cycle and some models[J]. Theoretical Biology Medical Modelling, 2005, 2(1):4-9.
[9]	Bedrossian M, Lindensmith C, Nadeau J L. Digital holographic microscopy, a method for detection of microorganisms in plume samples from enceladus and other icy worlds[J]. Astrobiology, 2017, 17(9):913-925.
[10]	Hsu W C, Su J W, Chang C C, et al. Investigating the backscattering characteristics of individual normal and cancerous cells based on experimentally determined three-dimensional refractive index distributions[C]//SPIE, 2012, 8553:855310.
[11]	Lee S Y, Park H J, Kim K, et al. Refractive index tomograms and dynamic membrane fluctuations of red blood cells from patients with diabetes mellitus[J]. Scientific Reports, 2017, 7:1039.
[12]	Haifler M, Girshovitz P, Dardikman G, et al. Interferometric phase microscopy for label-free morphological evaluation of sperm cells[J]. Fertility and Seterility, 2015, 104(1):43-47.
[13]	Shaked N T, Satterwhite L L, Telen M J, et al. Quantitative microscopy and nanoscopy of sickle red blood cells performed by wide field digital interferometry[J]. Journal of Biomedical Optics, 2011, 16(3):030506.
[14]	Mico V, Zalevsky Z, Garca J. Common-path phase-shifting digital holographic microscopy:A way to quantitative phase imaging and superresolution[J]. Optics Communications, 2008, 281(17):4273-4281.
[15]	Jiang H Z, Zhao J L, Di J L, et al. Numerically correcting the joint misplacement of the sub-holograms in spatial synthetic aperture digital Fresnel holography[J]. Optics Express, 2009, 17(21):18836-18842.
[16]	Schwarz C J, Kuznetsova Y, Brueck S R J. Imaging interferometric microscopy[J]. Optics Letters, 2003, 28(16):1424-1426.
[17]	Yuan C, Situ G, Pedrini G, et al. Resolution improvement in digital holography by angular and polarization multiplexing[J]. Applied Optics, 2011, 50(7):B6-B11.
[18]	Mico V, Zalevsky Z, Garcia-Martinez P, et al. Single-step superresolution by interferometric imaging[J]. Optics Express, 2004, 12(12):2589-2596.
[19]	Hillman T R, Gutzler T, Alexandrov S A, et al. High-resolution, wide-field object reconstruction with synthetic aperture Fourier holographic optical microscopy[J]. Optics Express, 2009, 17(10):7873-7892.
[20]	Mic V, Zalevsky Z, Ferreira C, et al. Superresolution digital holographic microscopy for three-dimensional samples[J]. Optics Express, 2008, 16(23):19260-19270.
[21]	Chowdhury S, Izatt J. Structured illumination quantitative phase microscopy for enhanced resolution amplitude and phase imaging[J]. Biomedical Optics Express, 2013, 4(10):1795-1805.
[22]	Gao P, Pedrini G, Osten W. Structured illumination for resolution enhancement and autofocusing in digital holographic microscopy[J]. Optics Letters, 2013, 38(8):1328-1330.
[23]	Gao P, Yao B L, Min J W, et al. Autofocusing of digital holographic microscopy based on off-axis illuminations[J]. Optics Letters, 2012, 37(17):3630-3632.
[24]	Goodman J. Speckle Phenomena in Optics:Theory and Applications[M]. American:Roberts Company, 2006.
[25]	Tiziani H J, Pedrini G. From speckle pattern photography to digital holographic interferometry[Invited] [J]. Applied Optics, 2013, 52(1):30-44.
[26]	Garca J, Zalevsky Z, Fixler D. Synthetic aperture superresolution by speckle pattern projection[J]. Optics Express, 2005, 13(16):6073-6078.
[27]	Park Y, Choi W, Yaqoob Z, et al. Speckle-field digital holographic microscopy[J]. Optics Express, 2009, 17(15):12285-12292.
[28]	Zheng J J, Gao P, Yao B L, et al. Digital holographic microscopy with phase-shift-free structured illumination[J]. Photonics Research, 2014, 2(3):87-91.
[29]	Ou X, Horstmeyer R, Zheng G, et al. High numerical aperture Fourier ptychography:Principle, implementation and characterization[J]. Optics Express, 2015, 23(3):3472-3491.
[30]	Faulkner H M L, Rodenburg J. Movable aperture lensless transmission microscopy:A novel phase retrieval algorithm[J]. Physical Review Letters, 2004, 93(2):023903.
[31]	Hoppe W. Beugung im inhomogenen Primrstrahlwellenfeld. I. Prinzip einer phasenmessung von elektronenbeungung-sinterferenzen[J]. Acta Crystallographica, 1969, 25(4):495-501.
[32]	Ou X, Horstmeyer R, Yang C, et al. Quantitative phase imaging via Fourier ptychographic microscopy[J]. Optics Letters, 2013, 38(22):4845-4848.
[33]	Zheng G A, Horstmeyer R, Yang C. Wide-field, high-resolution Fourier ptychographic microscopy[J]. Nature Photonics, 2013, 7:739-745.
[34]	Tian L, Liu Z, Yeh L-H, et al. Computational illumination for high-speed in vitro Fourier ptychographic microscopy[J]. Optica, 2015, 2(10):904-911.
[35]	He X, Liu C, Zhu J. Single-shot Fourier ptychography based on diffractive beam splitting[J]. Optics Letters, 2018, 43(2):214-217.
[36]	Tian L, Li X, Ramchandran K, et al. Multiplexed coded illumination for Fourier ptychography with an LED array microscope[J]. Biomedical Optics Express, 2014, 5(7):2376-2389.
[37]	Sun J S, Zuo C, Zhang L, et al. Resolution-enhanced Fourier ptychographic microscopy based on high-numerical-aperture illuminations[J]. Scientific Reports, 2017, 7:1187.
[38]	Maiden A M, Humphry M J, Zhang F, et al. Superresolution imaging via ptychography[J]. Journal of the Optical Society of America A, 2011, 28(4):604-612.
[39]	Thibault P, Menzel A. Reconstructing state mixtures from diffraction measurements[J]. Nature, 2013, 494:68.
[40]	Fienup J R. Reconstruction of an object from the modulus of its Fourier transform[J]. Optics Letters, 1978, 3(1):27-29.
[41]	Liu Cheng, Pan Xingchen. Coherent diffractive imaging based on the multiple beam illumination with cross grating[J]. Acta Physica Sinica, 2013, 62(18):184204.
[42]	Fan Jiadong, Jiang Huaidong. Coherent X-ray diffraction imaging and its applications in materials science and biology[J]. Acta Physica Sinica, 2012, 61(21):218702.
[43]	Gao P, Pedrini G, Zuo C, et al. Phase retrieval using spatially modulated illumination[J]. Optics Letters, 2014, 39(12):3615-3618.
[44]	Zhang Jianlin, Sun Jiasong, Chen Qian, et al. Adaptive pixel-super-resolved lensfree in-line digital holography for wide-field on-chip microscopy[J]. Scientific Reports, 2017, 7:11777. (in Chinese)
[45]	Wu Y, Zhang Y, Luo W, et al. Demosaiced pixel super-resolution for multiplexed holographic color imaging[J]. Scientific Reports, 2016, 6:28601.
[46]	Luo W, Greenbaum A, Zhang Y, et al. Synthetic aperture-based on-chip microscopy[J]. Light:Science Applications, 2015, 4:e261.
[47]	Stockmar M, Cloetens P, Zanette I, et al. Near-field ptychography:phase retrieval for inline holography using a structured illumination[J]. Scientific Reports, 2013, 3:1927.
[48]	Claus D, Rodenburg J M. Pixel size adjustment in coherent diffractive imaging within the Rayleigh-Sommerfeld regime[J]. Applied Optics, 2015, 54(8):1936-1944.
[49]	Bishara W, Su T-W, Coskun A F, et al. Lensfree on-chip microscopy over a wide field-of-view using pixel super-resolution[J]. Optics Express, 2010, 18(11):11181-11191.
[50]	Greenbaum A, Luo W, Khademhosseinieh B, et al. Increased space-bandwidth product in pixel super-resolved lensfree on-chip microscopy[J]. Scientific Reports, 2013, 3:1717.
[51]	Rivenson Y, Grcs Z, Gnaydin H, et al. Deep learning microscopy[J]. Optica, 2017, 4(11):1437-1443.
[52]	Su T, Xue L, Ozcan A. High-throughput lensfree 3D tracking of human sperms reveals rare statistics of helical trajectories 2012[J]. Nature Photonics, 2013, 7:739-745.

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通讯作者: 陈斌, bchen63@163.com

1.
沈阳化工大学材料科学与工程学院沈阳 110142

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Review of resolution enhancement technologies in quantitative phase microscopy

1. School of Physics and Optoelectronic Engineering,Xidian University,Xi'an 710171,China;

2. State Key Laboratory of Transient Optics and Photonics,Xi'an Institute of Optics and Precision Mechanics,Chinese Academy of Sciences,Xi'an 710119,China;

3. College of Physics and Information Technology,Shaanxi Normal University,Xi'an 710119,China

Received Date: 2019-04-05

Rev Recd Date: 2019-06-15

Publish Date: 2019-06-25

Key words:

Abstract: Quantitative Phase Microscopy (QPM), which combines phase imaging and optical microscopy, has been acting as a fast, non-destructive, and high-resolution methodology to measure the 3D morphology of reflective samples, as well as the inner structure or the refractive index of transparent samples. Similar to other diffraction-limited imaging systems, QPM suffers from the contradiction between spatial resolution and field of view (FOV). Therefore, how to achieve high spatial resolution in a large FOV has attracted a lot of attentions in the field of optical microscopy. In recent years, people utilized off-axis illumination, speckle illumination, structural illumination, and sub-pixel technology to synthesize a larger numerical aperture (SNA), and consequently enhanced the resolution of QPM. The resolution enhancement technologies of QPM were reviewed in this paper. The advantages and limitations of different methods were analyzed.

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Reference (52)

[1]	Platt B C, Shack R. History and principles of Shack-Hartmann wavefront sensing[J]. Journal of Refractive Surgery, 2001, 17(5):S573-S580.
[2]	Bon P, Maucort G, Wattellier B, et al. Quadriwave lateral shearing interferometry for quantitative phase microscopy of living cells[J]. Optics Express, 2009, 17(15):13080-13094.
[3]	Wei Q, Li Y, Vargas J, et al. Principal component analysis-based quantitative differential interference contrast microscopy[J]. Optics Letters, 2019, 44(1):45-48.
[4]	Cuche E, Bevilacqua F, Depeursinge C. Digital holography for quantitative phase-contrast imaging[J]. Optics Letters, 1999, 24(5):291-293.
[5]	Waheb B, Ting-Wei S, Coskun A F, et al. Lensfree on-chip microscopy over a wide field-of-view using pixel super-resolution[J]. Optics Express, 2010, 18(11):11181-11191.
[6]	Kyoohyun K, Hyeok Y, Monica D S, et al. High-resolution three-dimensional imaging of red blood cells parasitized by Plasmodium falciparum and in situ hemozoin crystals using optical diffraction tomography[J]. Journal of Biomedical Optics, 2014, 19(1):011005-011018.
[7]	Marquet P, Depeursinge C, Magistretti P J. Review of quantitative phase-digital holographic microscopy:promising novel imaging technique to resolve neuronal network activity and identify cellular biomarkers of psychiatric disorders[J]. Neurophotonics, 2014, 1(2):020901-020915.
[8]	Mitchison J M. Single cell studies of the cell cycle and some models[J]. Theoretical Biology Medical Modelling, 2005, 2(1):4-9.
[9]	Bedrossian M, Lindensmith C, Nadeau J L. Digital holographic microscopy, a method for detection of microorganisms in plume samples from enceladus and other icy worlds[J]. Astrobiology, 2017, 17(9):913-925.
[10]	Hsu W C, Su J W, Chang C C, et al. Investigating the backscattering characteristics of individual normal and cancerous cells based on experimentally determined three-dimensional refractive index distributions[C]//SPIE, 2012, 8553:855310.
[11]	Lee S Y, Park H J, Kim K, et al. Refractive index tomograms and dynamic membrane fluctuations of red blood cells from patients with diabetes mellitus[J]. Scientific Reports, 2017, 7:1039.
[12]	Haifler M, Girshovitz P, Dardikman G, et al. Interferometric phase microscopy for label-free morphological evaluation of sperm cells[J]. Fertility and Seterility, 2015, 104(1):43-47.
[13]	Shaked N T, Satterwhite L L, Telen M J, et al. Quantitative microscopy and nanoscopy of sickle red blood cells performed by wide field digital interferometry[J]. Journal of Biomedical Optics, 2011, 16(3):030506.
[14]	Mico V, Zalevsky Z, Garca J. Common-path phase-shifting digital holographic microscopy:A way to quantitative phase imaging and superresolution[J]. Optics Communications, 2008, 281(17):4273-4281.
[15]	Jiang H Z, Zhao J L, Di J L, et al. Numerically correcting the joint misplacement of the sub-holograms in spatial synthetic aperture digital Fresnel holography[J]. Optics Express, 2009, 17(21):18836-18842.
[16]	Schwarz C J, Kuznetsova Y, Brueck S R J. Imaging interferometric microscopy[J]. Optics Letters, 2003, 28(16):1424-1426.
[17]	Yuan C, Situ G, Pedrini G, et al. Resolution improvement in digital holography by angular and polarization multiplexing[J]. Applied Optics, 2011, 50(7):B6-B11.
[18]	Mico V, Zalevsky Z, Garcia-Martinez P, et al. Single-step superresolution by interferometric imaging[J]. Optics Express, 2004, 12(12):2589-2596.
[19]	Hillman T R, Gutzler T, Alexandrov S A, et al. High-resolution, wide-field object reconstruction with synthetic aperture Fourier holographic optical microscopy[J]. Optics Express, 2009, 17(10):7873-7892.
[20]	Mic V, Zalevsky Z, Ferreira C, et al. Superresolution digital holographic microscopy for three-dimensional samples[J]. Optics Express, 2008, 16(23):19260-19270.
[21]	Chowdhury S, Izatt J. Structured illumination quantitative phase microscopy for enhanced resolution amplitude and phase imaging[J]. Biomedical Optics Express, 2013, 4(10):1795-1805.
[22]	Gao P, Pedrini G, Osten W. Structured illumination for resolution enhancement and autofocusing in digital holographic microscopy[J]. Optics Letters, 2013, 38(8):1328-1330.
[23]	Gao P, Yao B L, Min J W, et al. Autofocusing of digital holographic microscopy based on off-axis illuminations[J]. Optics Letters, 2012, 37(17):3630-3632.
[24]	Goodman J. Speckle Phenomena in Optics:Theory and Applications[M]. American:Roberts Company, 2006.
[25]	Tiziani H J, Pedrini G. From speckle pattern photography to digital holographic interferometry[Invited] [J]. Applied Optics, 2013, 52(1):30-44.
[26]	Garca J, Zalevsky Z, Fixler D. Synthetic aperture superresolution by speckle pattern projection[J]. Optics Express, 2005, 13(16):6073-6078.
[27]	Park Y, Choi W, Yaqoob Z, et al. Speckle-field digital holographic microscopy[J]. Optics Express, 2009, 17(15):12285-12292.
[28]	Zheng J J, Gao P, Yao B L, et al. Digital holographic microscopy with phase-shift-free structured illumination[J]. Photonics Research, 2014, 2(3):87-91.
[29]	Ou X, Horstmeyer R, Zheng G, et al. High numerical aperture Fourier ptychography:Principle, implementation and characterization[J]. Optics Express, 2015, 23(3):3472-3491.
[30]	Faulkner H M L, Rodenburg J. Movable aperture lensless transmission microscopy:A novel phase retrieval algorithm[J]. Physical Review Letters, 2004, 93(2):023903.
[31]	Hoppe W. Beugung im inhomogenen Primrstrahlwellenfeld. I. Prinzip einer phasenmessung von elektronenbeungung-sinterferenzen[J]. Acta Crystallographica, 1969, 25(4):495-501.
[32]	Ou X, Horstmeyer R, Yang C, et al. Quantitative phase imaging via Fourier ptychographic microscopy[J]. Optics Letters, 2013, 38(22):4845-4848.
[33]	Zheng G A, Horstmeyer R, Yang C. Wide-field, high-resolution Fourier ptychographic microscopy[J]. Nature Photonics, 2013, 7:739-745.
[34]	Tian L, Liu Z, Yeh L-H, et al. Computational illumination for high-speed in vitro Fourier ptychographic microscopy[J]. Optica, 2015, 2(10):904-911.
[35]	He X, Liu C, Zhu J. Single-shot Fourier ptychography based on diffractive beam splitting[J]. Optics Letters, 2018, 43(2):214-217.
[36]	Tian L, Li X, Ramchandran K, et al. Multiplexed coded illumination for Fourier ptychography with an LED array microscope[J]. Biomedical Optics Express, 2014, 5(7):2376-2389.
[37]	Sun J S, Zuo C, Zhang L, et al. Resolution-enhanced Fourier ptychographic microscopy based on high-numerical-aperture illuminations[J]. Scientific Reports, 2017, 7:1187.
[38]	Maiden A M, Humphry M J, Zhang F, et al. Superresolution imaging via ptychography[J]. Journal of the Optical Society of America A, 2011, 28(4):604-612.
[39]	Thibault P, Menzel A. Reconstructing state mixtures from diffraction measurements[J]. Nature, 2013, 494:68.
[40]	Fienup J R. Reconstruction of an object from the modulus of its Fourier transform[J]. Optics Letters, 1978, 3(1):27-29.
[41]	Liu Cheng, Pan Xingchen. Coherent diffractive imaging based on the multiple beam illumination with cross grating[J]. Acta Physica Sinica, 2013, 62(18):184204.
[42]	Fan Jiadong, Jiang Huaidong. Coherent X-ray diffraction imaging and its applications in materials science and biology[J]. Acta Physica Sinica, 2012, 61(21):218702.
[43]	Gao P, Pedrini G, Zuo C, et al. Phase retrieval using spatially modulated illumination[J]. Optics Letters, 2014, 39(12):3615-3618.
[44]	Zhang Jianlin, Sun Jiasong, Chen Qian, et al. Adaptive pixel-super-resolved lensfree in-line digital holography for wide-field on-chip microscopy[J]. Scientific Reports, 2017, 7:11777. (in Chinese)
[45]	Wu Y, Zhang Y, Luo W, et al. Demosaiced pixel super-resolution for multiplexed holographic color imaging[J]. Scientific Reports, 2016, 6:28601.
[46]	Luo W, Greenbaum A, Zhang Y, et al. Synthetic aperture-based on-chip microscopy[J]. Light:Science Applications, 2015, 4:e261.
[47]	Stockmar M, Cloetens P, Zanette I, et al. Near-field ptychography:phase retrieval for inline holography using a structured illumination[J]. Scientific Reports, 2013, 3:1927.
[48]	Claus D, Rodenburg J M. Pixel size adjustment in coherent diffractive imaging within the Rayleigh-Sommerfeld regime[J]. Applied Optics, 2015, 54(8):1936-1944.
[49]	Bishara W, Su T-W, Coskun A F, et al. Lensfree on-chip microscopy over a wide field-of-view using pixel super-resolution[J]. Optics Express, 2010, 18(11):11181-11191.
[50]	Greenbaum A, Luo W, Khademhosseinieh B, et al. Increased space-bandwidth product in pixel super-resolved lensfree on-chip microscopy[J]. Scientific Reports, 2013, 3:1717.
[51]	Rivenson Y, Grcs Z, Gnaydin H, et al. Deep learning microscopy[J]. Optica, 2017, 4(11):1437-1443.
[52]	Su T, Xue L, Ozcan A. High-throughput lensfree 3D tracking of human sperms reveals rare statistics of helical trajectories 2012[J]. Nature Photonics, 2013, 7:739-745.

Review of resolution enhancement technologies in quantitative phase microscopy

doi: 10.3788/IRLA201948.0603007

Abstract

References

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通讯作者: 陈斌, bchen63@163.com

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